Multiple sclerosis and related disorders

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Comparative Efficacy of Relapsing Multiple Sclerosis Therapies: Model-Based Meta-Analyses for Confirmed Disability Accumulation and Annualized Relapse Rate. Brian Hennessy, Matthew L. Zierhut, Hilke Kracker, Alexander Keenan, Tatiana Sidorenko. Published online: May 23, 2022. The success of clinical trials of selective B‐cell depletion in patients with relapsing multiple sclerosis (RMS) and primary progressive MS (PPMS) have led to a conceptual shift in the understanding of MS pathogenesis, away from the classical model in which T cells were the sole central actors, and towards a more complex paradigm with B cells having an essential role in. Multiple sclerosis (MS) and dementia in Alzheimer’s disease are not the same diagnosis. Dementia causes more severe memory, thinking, or mobility changes than. Multiple Sclerosis and Related Disorders Supports open access 5.0 CiteScore 4.339 Impact Factor Articles & Issues Sign in to set up alerts Submit your article Guide for authors Volume 30 Pages 1-294, A1-A2 (May 2019) Download full issue Previous vol/issue Next vol/issue Actions for selected articles Contents. ejculm
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Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders.

Neuroimmunology: Multiple Sclerosis, Autoimmune Neurology and Related Diseases. This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune. Read the latest articles of Multiple Sclerosis and Related Disorders at ScienceDirect.com, Elsevier's leading platform of peer-reviewed scholarly literature.

Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS. Multiple sclerosis, or MS, is a terrifying disease. While generally rare (1 in every 1,000 women, and 1 in every 3,000 men), the illness can cause a host of problems, including anxiety. Get a Better Understanding of Your Anxiety. Peoples’ experience of MS varies widely. The scleroses can affect any part of the brain, and that means that some.

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Takeaway. Multiple sclerosis (MS) is a chronic condition that affects the central nervous system. MS is considered to be an immune-mediated disease, which is a disease that causes the body’s. The success of clinical trials of selective B‐cell depletion in patients with relapsing multiple sclerosis (RMS) and primary progressive MS (PPMS) have led to a conceptual shift in the understanding of MS pathogenesis, away from the classical model in which T cells were the sole central actors, and towards a more complex paradigm with B cells having an essential role in. Luo, D., Wang, J., Zhang, X., Rang, X., Xu, C., & Fu, J. (2020). Identification and functional analysis of specific MS risk miRNAs and their target genes.

This neuroinflammatory disease can prevent you from getting a good night’s rest. The causes of MS-related sleep problems are more than just physical discomfort for many patients. Talk to your doctor about one or more of the following possible causes if. Multiple sclerosis is the most common chronic disabling disease of the central nervous system in young adults. Objective This article summarises the diagnosis, management and prognosis of multiple sclerosis. Discussion Multiple sclerosis usually starts with an acute episode of neurological disturbance, termed a ‘clinically isolated.

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Background Multiple sclerosis (MS) is characterized by phenotypical heterogeneity, partly resulting from demographic and environmental risk factors. Socio-economic factors and the characteristics of local MS facilities might also play a part. Methods This study included patients with a confirmed MS diagnosis enrolled in the Italian MS and Related Disorders.

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Striking similarities between patients with multiple sclerosis and a type of schizophrenia suggest the disorders are related, according to a review of a number of studies. Dr. Boris M. Arneth.

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Researchers sought to determine if physical exercise has a positive effect on multiple sclerosis fatigue and which type of exercise has the largest effect on fatigue, also based on disease severity. Both of these conditions affect the brain and the spine. However, in MS, demyelinating lesions can be seen in the brain and spine by MRI, while in ALS the neuronal damage is not able to be seen on imaging. MS, but not ALS, can also involve the optic nerves (the nerves that control vision). In addition, the disease pathophysiology (biological.

The pen multiple sclerosis and related disorders center is a dynamic group of professionals who are committed to caring for people with multiple sclerosis. This is what we do every day. A multidisciplinary team is so important in the care of people living with multiple sclerosis because M. S. Encompasses the whole body. Multiple sclerosis presents patients with a number of symptoms that can disrupt everyday life. During an episode for those with relapsing-remitting MS, or those with one of the progressive MS forms with constant symptoms, obtaining a diagnosis that allows the patient to work with doctors and therapists to create a treatment and management regimen is crucial to. A review published in Multiple Sclerosis and Related Disorders provided a comprehensive overview of the risk factors, prevalence, management and complications of UTIs in this patient group. 1.

Contact the Pediatric Multiple Sclerosis and Related Disorders Program. 617-355-6388. International +1-617-355-5209. Request an Appointment Request a Second Opinion. Visit 300 Longwood Avenue Boston, MA 02115. Call 617-355-6000..

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An autoimmune disorder in which white blood cells and antibodies primarily attack the optic nerves and the spinal cord, but may also attack the brain. Learn More Schilder's Disease A very rare, progressive, degenerative, demyelinating disorder of the central nervous system that usually begins in childhood. Learn More Transverse Myelitis.

Get this from a library! Multiple sclerosis and related disorders : clinical guide to diagnosis, medical management, and rehabilitation. [Alexander Rae-Grant; Robert Fox; François Béthoux;] -- Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients.

Multiple Sclerosis and Related Disorders is a wide ranging international journal supported by key researchers from all neuroscience domains that focus on MS and associated disease of the central nervous system. The primary aim of this new journal is the rapid publication of high quality original research in the field. Multiple sclerosis can really take a toll on your sleep. Get a better understanding of MS-related sleep problems. Partial or complete loss of vision, usually in one eye at a time, often with pain during eye movement. Prolonged double vision. Blurry vision. Multiple sclerosis symptoms may also include: Slurred speech. Fatigue. Dizziness.. There is no cure for multiple sclerosis. Treatment typically focuses on speeding recovery from attacks, slowing the progression of the disease and managing MS symptoms. Some people have such mild symptoms that no treatment is necessary. Multiple sclerosis research laboratory at Mayo Clinic.

An autoimmune disorder in which white blood cells and antibodies primarily attack the optic nerves and the spinal cord, but may also attack the brain. Learn More Schilder's Disease A very rare, progressive, degenerative, demyelinating disorder of the central nervous system that usually begins in childhood. Learn More Transverse Myelitis.

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Answer. MS is a disease that attacks the central nervous system (CNS), which is made up of the optic nerves, brain and spinal cord. In patients with MS, the immune system attacks healthy tissue in the CNS. This damage interferes with the transmission of nerve signals between the brain and spinal cord and the rest of the body. This neuroinflammatory disease can prevent you from getting a good night’s rest. The causes of MS-related sleep problems are more than just physical discomfort for many patients. Talk to your doctor about one or more of the following possible causes if.

Multiple sclerosis (MS) is an inflammatory neurological condition that affects the central nervous systems, causing many physical and neuropsychological problems for sufferers. Most people are diagnosed between the ages of 20.

Doctors use it to look for high levels of proteins and other substances that are signs of the disease. It can help diagnose MS, but it, too, isn’t absolute proof. Know what to expect with a.

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Multiple sclerosis (MS) is a complex neurologic disease caused by both genetic and environmental risk factors. To our knowledge, few studies have investigated the relationship between alcohol and MS risk, and these have been limited by small sample sizes and inconsistent results. 1-3 Hedström and colleagues 4 reported that alcohol consumption exhibits a dose.

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Doctors use it to look for high levels of proteins and other substances that are signs of the disease. It can help diagnose MS, but it, too, isn’t absolute proof. Know what to expect with a. Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS.

Diagnosing and treating multiple sclerosis Autoimmune encephalitis Neuromyelitis optica spectrum disorder (NMOSD) Transverse myelitis Genetic counseling: Some of these disorders may be passed down in families. Expert medical geneticists at OHSU's Neuro Genetics Clinic can help you identify and manage risk. Optic neuritis.

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Patients with multiple sclerosis (MS) often report fatigue, poor sleep and complaint of sleep disorders. Neurofilament light chain (NF-L) has been identified as a potential biomarker for disease progression in MS patients. In this study, we aimed to evaluate sleep characteristics in MS patients and its relationship with the level of serum NF-L. In the present study carried out. Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system ... Signs, and Therapy in Multiple Sclerosis. Rae-Grant A, Fox R, Bethoux F. Multiple Sclerosis and Related Disorders: Diagnosis, Medical Management, and Rehabilitation. Demos Medical Publishing; 2013. 179. Your care will be guided by the deep knowledge and experience of our physicians, who focus exclusively on neuroinflammatory conditions, including: Multiple sclerosis (MS) Neuromyelitis Optica (NMO) Spectrum Disorder Myelin Oligodendrocyte Glycoprotein (MOG)-Antibody Associated Disease. Multiple sclerosis, or MS, is a terrifying disease. While generally rare (1 in every 1,000 women, and 1 in every 3,000 men), the illness can cause a host of problems, including anxiety. Get a Better Understanding of Your Anxiety. Peoples’ experience of MS varies widely. The scleroses can affect any part of the brain, and that means that some.

submission of a paper to multiple sclerosis and related disorders will be held to imply that it represents original research not previously published (except in the form of an abstract or preliminary report), that it is not being considered for publication elsewhere, and that if accepted by multiple sclerosis and related disorders it will not be. Multiple sclerosis (MS) is a chronic disease that affects the central nervous system. It affects more than 25,000 people in Australia and is 3 times more common in women than in men. MS means there is damage to the protective sheath (known as myelin) that surrounds the nerve fibres in the brain and spinal cord.

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In 2018, Ramsey became the first person with multiple sclerosis to finish the 930-mile Race Across the West as a solo rider. Not only that, he finished third for men under 50, riding from Oceanside, California, to Durango, Colorado, in three days, four hours and 47 minutes. Learn why his OHSU doctors say Ramsey backs up research findings on MS. An unpredictable disease of the central nervous system, multiple sclerosis (MS) can range from relatively benign to somewhat disabling to devastating, as communication between the brain and other parts of the body is disrupted. Many investigators believe MS to be an autoimmune disease -- one in which the body, through its immune system, launches a. Central neuropathic pain is common in multiple sclerosis (MS), and its prevalence increases with physical disability. Sufficient evidence links dysesthetic pain, trigeminal neuralgia, Lhermitte’s sign, and painful tonics spasms to plaque formation in the spinal cord and brain, whereas the association with headache and back pain remains unclear. Management varies. Multiple sclerosis (MS) and dementia in Alzheimer’s disease are not the same diagnosis. Dementia causes more severe memory, thinking, or mobility changes than.

Multiple sclerosis (MS) is a long-lasting (chronic) disease of the central nervous system. It is thought to be an autoimmune disorder, a condition in which the body attacks itself by mistake. MS is an unpredictable disease that affects people differently. Some people with MS may have only mild symptoms. Others may lose their ability to see. .

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The suspicion for this metabolic disorder arises when patients present with an elevated blood ammonia level and neurological manifestation without underlying hepatocellular dysfunction. 3 Postpartum decompensation is well recognised in urea cycle disorders, and in our case this presentation related to stress accompanied by hyperammonemia is what led us to.

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Labiano-Fontcuberta A, Mitchell AJ, Moreno-Garcia S, Peurtas-Martin V, Benito-Leon J. Impact of anger on the health-related quality of life of multiple sclerosis patients. Mult Scler. 2015 Apr;21(5):630-41. doi: 10.1177/135245851454939. Mental Health Disorder Treatment Guidelines and Consumer Guides. Anger Symptoms, Causes, and Effects. Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. Consensus definitions proposed for pediatric multiple sclerosis and related disorders Lauren B. Krupp, MD; Brenda Banwell, MD; and Silvia Tenembaum, MD; for the International Pediatric MS Study Group* Abstract—Background: The CNS inflammatory demyelinating disorders of childhood include both self-limited and life- long conditions, which can be indistinguishable at the time of.

ds: Retrospective review of 185 patients with MD and DD seen at our center over a period of 7 years. Clinical imaging, medications, and therapeutic responses to both MD and DD treatments were reviewed. Results: Of the 185 patients, 62 were excluded because of a diagnosis of spasticity without any other MD. One hundred twenty three patients with DD (75% female, age. This neuroinflammatory disease can prevent you from getting a good night’s rest. The causes of MS-related sleep problems are more than just physical discomfort for many patients. Talk to your doctor about one or more of the following possible causes if.

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Multiple Sclerosis and Related Disorders features: Comprehensive clinical reference for all members of the MS care team Focus on practical approaches to diagnosis, treatment, counseling, and. Contact the Pediatric Multiple Sclerosis and Related Disorders Program. 617-355-6388. International +1-617-355-5209. Request an Appointment Request a Second Opinion. Visit 300 Longwood Avenue Boston, MA 02115. Call 617-355-6000.. Bar-Or, A. (2016). Multiple sclerosis and related disorders: evolving pathophysiologic insights. The Lancet Neurology, 15(1), 9–11. doi:10.1016/s1474-4422(15)00342-7.

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Revised and updated second edition of Multiple Sclerosis and Related Disorders: Clinical Guide to Diagnosis, Medical Management, and Rehabilitation, the only comprehensive but practical source of core information on multiple sclerosis and other demyelinating disorders.Intended as a ready reference for clinicians who provide ongoing care to MS patients, this book combines evidence.

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11 years ago
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Answer. MS is a disease that attacks the central nervous system (CNS), which is made up of the optic nerves, brain and spinal cord. In patients with MS, the immune system attacks healthy tissue in the CNS. This damage interferes with the transmission of nerve signals between the brain and spinal cord and the rest of the body.

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More precise definition of the clinical pre-sentations of NMOSD allow it to be diagnosed in the presence of at least one of the six core clinical characteristics, along with detection of AQP4-ab and ruling out alternative diagnoses (Wingerchuk et al., E. Carnero Contentti, et al. Multiple Sclerosis and Related Disorders 45 (2020) 102428 2. Vision problems can be one of the first signs of multiple sclerosis (MS) in some people. A common symptom is optic neuritis, or inflammation of the optic nerve (which connects the eye and brain ). It can cause pain, vision loss, double vision, blurry vision and dim color vision. Weakness of eye muscles and uncontrolled eye movements can also be.

Multiple sclerosis (MS) ... But many of these problems aren't specific to MS and can be caused by a wide range of other conditions, ... This could be directly related to MS, or it could be the result of living with the condition. Bladder problems. Bladder problems are common in MS.

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Impairments in bladder function with multiple sclerosis (MS) are common and may affect up to 78 to 90 percent of patients during the course of MS. The prevalence of bowel dysfunction in MS is estimated to be about 68 percent of patients. Bladder and bowel symptoms are relatively common in MS and can be treated. Multiple Sclerosis Journal is a peer-reviewed international journal that focuses on all aspects of multiple sclerosis, neuromyelitis optica and other related autoimmune diseases of the central nervous system. The journal for your research in the following areas: Biologic basis; Epidemology and genetics; Clinical and Neuroimaging; Therapeutics.

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ds: Retrospective review of 185 patients with MD and DD seen at our center over a period of 7 years. Clinical imaging, medications, and therapeutic responses to both MD and DD treatments were reviewed. Results: Of the 185 patients, 62 were excluded because of a diagnosis of spasticity without any other MD. One hundred twenty three patients with DD (75% female, age.

Fox R, Rae-Grant A, Béthoux F 2018, ‘Multiple sclerosis and related disorders: clinical guide to diagnosis, medical management, and rehabilitation’ (Second edition), Springer Publishing Company. Halper J, Harris C 2016, ‘ Nursing practice in multiple sclerosis: a core curriculum ’ (Fourth edition), Springer Publishing Company. Multiple Sclerosis is an area of ever expanding research and escalating publications.Multiple Sclerosis and Related Disorders is a wide ranging international journal supported by key researchers from all neuroscience domains that focus on MS and associated disease of the central nervous system.The primary aim of this new journal is the rapid publication of high.

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11 years ago
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Previous studies of personality change in multiple sclerosis (MS) relied on brief, nonstandardized assessments or tests that are confounded with symptoms of acute psychiatric disorder. Objectives of the present study were to evaluate character change in MS by using comprehensive trait measures of personality and to determine if there is an association. Multiple Sclerosis is an area of ever expanding research and escalating publications. Multiple Sclerosis and Related Disorders is a wide ranging international journal supported by key researchers from all neuroscience domains that focus on MS and associated disease of the central nervous system. The primary aim of this new journal is the rapid.

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Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS. Contact the Pediatric Multiple Sclerosis and Related Disorders Program. 617-355-6388. International +1-617-355-5209. Request an Appointment Request a Second Opinion. Visit 300 Longwood Avenue Boston, MA 02115. Call 617-355-6000..

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11 years ago
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Multiple Sclerosis and Related Disorders is a wide ranging international journal supported by key researchers from all neuroscience domains that focus on MS and associated disease of the central nervous system. The primary aim of this new journal is the rapid publication of high quality original research in the field.

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10 years ago
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Answer. MS is a disease that attacks the central nervous system (CNS), which is made up of the optic nerves, brain and spinal cord. In patients with MS, the immune system attacks healthy tissue in the CNS. This damage interferes with the transmission of nerve signals between the brain and spinal cord and the rest of the body.

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10 years ago
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Multiple Sclerosis and Related Disorders features: Comprehensive clinical reference for all members of the MS care team Focus on practical approaches to diagnosis, treatment, counseling, and.

Multiple sclerosis, myelitis and other related disorders challenge families, who rise to the occasion by becoming care partners for their loved one. Patients rely heavily on their family caregivers, who often suffer tremendous stress, particularly.

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9 years ago
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Reply to  Robert Farrington

Diagnosing and treating multiple sclerosis. Autoimmune encephalitis. Neuromyelitis optica spectrum disorder (NMOSD) Transverse myelitis. Genetic counseling: Some of these disorders may be passed down in families. Expert medical geneticists at OHSU’s Neuro Genetics Clinic can help you identify and manage risk. Optic neuritis. Answer. MS is a disease that attacks the central nervous system (CNS), which is made up of the optic nerves, brain and spinal cord. In patients with MS, the immune system attacks healthy tissue in the CNS. This damage interferes with the transmission of nerve signals between the brain and spinal cord and the rest of the body.

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10 years ago
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9 years ago
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If you are an administrator for Multiple Sclerosis and Related Disorders, please get in touch to find out how you can verify the contributions of your editorial board members and more. Top reviewers on Publons (Manuscripts reviewed in last 12 months) (23) Steve Simpson, Jr..

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Multiple Sclerosis and Related Disorders has been ranked #90 over 156 related journals in the Neurology research category. The ranking percentile of Multiple Sclerosis and Related Disorders is around 42% in the field of Neurology. Multiple Sclerosis and Related Disorders Key Factor Analysis Related Journals. The emotional factors relating to changes in sexual function are quite complex. They may involve loss of self-esteem, depression, anxiety, anger and/or the stress of living with a chronic illness. Counseling — for you and your partner — by a mental health professional or trained sexual therapist can address both physiologic and psychological issues.

Corrigendum to ‘ Incidence and risk factors for venous thromboembolism during an acute attack in patients with neuromyelitis optica spectrum disorders’ [Multiple Sclerosis and Related Disorders 58 (2022) 103513] Juyuan Pan, Ruofan Zhu, Jie Lin, Xiang Li, Junhui Xia. Published online: July 27, 2022. 104058.

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9 years ago
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About the Book . Alexander Rae-Grant's name appears first in the previous edition. Book Synopsis . Revised and updated second edition of Multiple Sclerosis and Related Disorders: Clinical Guide to Diagnosis, Medical Management, and Rehabilitation, the only comprehensive but practical source of core information on multiple sclerosis and other demyelinating disorders.

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8 years ago
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7 years ago
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Revised and updated second edition of Multiple Sclerosis and Related Disorders: Clinical Guide to Diagnosis, Medical Management, and Rehabilitation, the only comprehensive but practical source of core information on multiple sclerosis and other demyelinating disorders.

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1 year ago
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